Re: [問題] depakine&dilantin
來源:http://www.drugs.com/drug_interactions.php
dilantin (phenytoin) and Depakote (divalproex sodium) (Moderate Drug-Drug)
MONITOR: Valproic acid (and its derivatives) may increase the pharmacologic
effects of phenytoin.
Toxicity may result, despite normal phenytoin levels.
The mechanism may be related to displacement of phenytoin from plasma
proteins.
Also, phenytoin may induce the CYP450 metabolism of valproic acid.
Similar interactions may occur with other hydantoins.
※ 引述《starhsueh (抹茶+牛奶)》之銘言:
: 晚安
: 昨天被學姊問為什麼這兩個(口服藥)必須要單獨給藥 不能與別的藥一起給
: 我是回答 會被其他藥物抵銷藥物作用
: 但學姊卻問我是被哪些藥物抵銷 我就不知道了
: 剛查了網路 都也是說不可跟其他藥物或食物一起吃
: 並沒有說明
: 請問有人知道的嗎
: 煩請告知 謝謝
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