Re: [閒聊] 藥理期中考
Metabolic Alkalosis
Administration of Diuretics (Except the Carbonic Anhydrase Inhibitors)
All diuretics cause increased flow of fluid along the tubules, usually
increasing flow in the distal and collecting tubules. This leads to increased
reabsorption of Na+ from these parts of the nephrons. Because the sodium
reabsorption here is coupled with H+ secretion, the enhanced sodium
reabsorption also leads to an increase in H+ secretion and an increase in
bicarbonate reabsorption. These changes lead to the development of alkalosis,
characterized by increased extracellular fluid bicarbonate concentration.
Gyuton 12e pp.392
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