Re: [求救] 想問免疫 抗原抗體反應的問題??
※ 引述《eriel (橘子數)》之銘言：
: 我覺得是不是要寫出ELISA或是Flow cytometry之類的抗體抗原技術，然後討論
: 之間的相同與相異處？
: 或者出題者目的其實是要考生瞭解抗體的一些特性：cross-reactivity or
: antibody affinity 跟 antibody avidity的不同？
: 這題目真的有點不太懂...
avidity: 指的是整個ab對整個抗原的結合能力
affinity: 指的是在一個antibody中 不同的complementory domain
對該epitope的結合力
找一段wikipedia的說明給你參考
In proteins, avidity is a term use to describe the combined strength of male
interactions. Avidity is distinct from affinity, which is a term used to
describe the strength of a single bond. As such, avidity is the combined
synergistic strength of bond affinities rather than the sum of bonds.
Avidity is commonly applied to antibody interaction. Where multiple, weak,
non-covalent bonds form between antigen and antibody. Individually, each bond
is quite readily broken, however when many are present at the same time the
overall effect results in synergistic, strong binding of antigen to antibody.
我不是很記得我有沒有講反 兩年沒念書了
有錯還請板上各位先進幫忙修改
建議你去翻隨便一本免疫學課本
都有很詳細的說明
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※ 編輯: Danielle 來自: 140.109.55.225 (11/07 16:38)
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