[問題] Ketorolac在NSAIDs中結構分類

看板pharmacist作者 (普拿疼)時間8年前 (2016/02/14 20:19), 編輯推噓6(604)
留言10則, 2人參與, 最新討論串1/1
如題 Ketorolac的結構分類? 維基百科寫說 Although its name does not suggest similarity with propionic acid derivatives (e.g. ketoprofen, flurbiprofen, naproxen, ibuprofen, carprofen etc.), ketorolac is an isostere of ketoprofen. More precisely, it is a dihydropyrrolizine carboxylic acid derivative structurally related to indomethacin. 所以Ketolor是和ketoprofen, flurbiprofen, naproxen, ibuprofen 同類屬propionic acid類衍生物, 還是和Diclofenac,Etodolac,Indomethacin,Sulindac屬Acetic acids類衍生物 (因為有ac結尾) ? 謝謝 -- ※ 發信站: 批踢踢實業坊(ptt.cc), 來自: 223.138.179.103 ※ 文章網址: https://www.ptt.cc/bbs/pharmacist/M.1455452340.A.5AF.html

02/14 21:31, , 1F
除了wiki,可以從這找結構式
02/14 21:31, 1F

02/14 21:31, , 2F

02/14 21:35, , 3F
然後找 ATC Code, ATC Code解釋http://goo.gl/XtQTSY
02/14 21:35, 3F

02/14 21:37, , 4F
M01AE03 - Ketoprofen
02/14 21:37, 4F

02/14 21:37, , 5F
M01AB15 - Ketorolac
02/14 21:37, 5F

02/14 21:37, , 6F
M01AB05 - Diclofenac
02/14 21:37, 6F

02/14 21:38, , 7F
所以應該歸類在acetic acids類衍生物, 有誤請指正
02/14 21:38, 7F

02/16 18:16, , 8F
@@我的blog??
02/16 18:16, 8F

02/16 19:04, , 9F
原來是作者,抱歉。
02/16 19:04, 9F

02/16 19:23, , 10F
不會,請用
02/16 19:23, 10F
文章代碼(AID): #1Mm72qMl (pharmacist)