[整理] 美國 NIH 網站顯示 HCQ 預防武漢肺炎有效
發稿單位:NIH
發稿時間:2021 Apr 20.
撰 稿 者:Raymond Chee Seong Seet etc.
原文連結:https://pubmed.ncbi.nlm.nih.gov/33864917/
Positive impact of oral hydroxychloroquine and povidone-iodine throat spray
for COVID-19 prophylaxis: An open-label randomized trial
Abstract
Background: We examined whether existing licensed pharmacotherapies could
reduce the spread of coronavirus disease 2019 (COVID-19).
Methods: An open-label parallel randomized controlled trial was performed
among healthy migrant workers quarantined in a large multi-storey dormitory
in Singapore. Forty clusters (each defined as individual floors of the
dormitory) were randomly assigned to receive a 42-day prophylaxis regimen of
either oral hydroxychloroquine (400 mg once, followed by 200 mg/day), oral
ivermectin (12 mg once), povidone-iodine throat spray (3 times/day, 270 μ
g/day), oral zinc (80 mg/day)/vitamin C (500 mg/day) combination, or oral
vitamin C, 500 mg/day. The primary outcome was laboratory evidence of
SARS-CoV-2 infection as shown by either: (1) a positive serologic test for
SARS-CoV-2 antibody on day 42, or (2) a positive PCR test for SARS-CoV-2 at
any time between baseline and day 42.
Results: A total of 3037 asymptomatic participants (mean age, 33.0 years; all
men) who were seronegative to SARS-CoV-2 at baseline were included in the
primary analysis. Follow-up was nearly complete (99.6%). Compared with
vitamin C, significant absolute risk reductions (%, 98.75% confidence
interval) were observed for oral hydroxychloroquine (21%, 2-42%) and
povidone-iodine throat spray (24%, 7-39%). No statistically significant
differences were observed with oral zinc/vitamin C combination (23%, -5 to
+41%) and ivermectin (5%, -10 to +22%). Interruptions due to side effects
were highest among participants who received zinc/vitamin C combination
(6.9%), followed by vitamin C (4.7%), povidone-iodine (2.0%), and
hydroxychloroquine (0.7%).
Conclusions: Chemoprophylaxis with either oral hydroxychloroquine or
povidone-iodine throat spray was superior to oral vitamin C in reducing
SARS-CoV-2 infection in young and healthy men.
我直接講結論,
HCQ 確實可以有效預防武漢肺炎,
效果比 vitamin C 好.
感想:
這篇文章我有先問 swattw 大,
他說不能用新聞發用整理發,
因為我要發之前我考慮到他已經過期,
不符合板規,
所以我才問 swattw 大,
既然他說用整理發,
那我就用整理發.
--
※ 發信站: 批踢踢實業坊(ptt.cc), 來自: 101.10.58.35 (臺灣)
※ 文章網址: https://www.ptt.cc/bbs/nCoV2019/M.1622044989.A.EFC.html
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奇怪,有的人就是不喜歡看版規在那邊砲。
第 7 條
[新聞]文章應有下列內容:
一、完整標題。
二、發稿單位。
三、發稿時間。
四、撰稿人。
五、原文連結。原文連結除超過一行以上,得用非盈利轉址以外,應填入原址。
我國新聞文章不得逾發稿後二日發文、外國新聞文章不得逾發稿後七日發文。
[整理][新聞]文章不得有下列內容:
一、與疫情或醫藥進展無直接相關。
二、歌頌、宣傳中國。
三、非本板所表列之來源。
※ 編輯: saveme (101.10.58.35 臺灣), 05/27/2021 09:54:09
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你還是沒有把版規看清楚,我用的是整理,不是新聞,而且我問過版主了,可見內文你都沒在看。
※ 編輯: saveme (101.10.58.35 臺灣), 05/27/2021 11:08:52
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