[國考] 醫學二85 請在sinx大那裡寫這題的進入
以下完全複製提供者的敘述
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"根據Harrison's Internal Medicine > Chapter 278. Polycystic Kidney Disease
and Other Inherited Tubular Disorders > Clinical Features 裡面一句話:
Phenotypic heterogeneity is a hallmark of ADPKD, as evidenced by family
members who share the same mutation but have a different clinical course.
Affected individuals are often asymptomatic into the fourth or fifth decade.
Presenting symptoms and signs include abdominal discomfort, hematuria,
urinary tract infection, incidental discovery of hypertension, abdominal
mass, elevated serum creatinine, or cystic kidneys on imaging studies (Fig.
278-1A and B ). Frequently the diagnosis is made prior to the onset of
symptoms, when asymptomatic members in affected families request screening.
In most patients, renal function declines progressively over the course of 10
–20 years from the time of diagnosis, but not everyone with ADPKD develops
ESRD.
大部份病人是因為家族有遺傳而自己去檢查出來的,而且句中出現In most patients,
renal function declines progressively over the course of 10–20 years from
the time of diagnosis,故得知(C)很多病人直到腎臟衰竭時才被發現。"
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不知可否請原作者附上參考來源的圖檔 謝謝
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