[情報] Oxycodone(氧可酮)
Oxycodone
(ox i KOE done)
M-Oxy, OxyContin, Oxyir, Percolone, Roxicodone
1
What is the most important information I should know about oxycodone?
‧ Do not crush, chew, or break controlled-release forms of oxycodone such
as Oxycontin. Swallow them whole. They are specially formulated to release
oxycodone slowly into your system. Breaking them would cause too much drug to
be released into the blood at one time leading to a potentially fatal dose of
oxycodone.
‧ Use caution when driving, operating machinery, or performing other
hazardous activities. Oxycodone will cause drowsiness or dizziness. If you
experience drowsiness or dizziness, avoid these activities.
‧ Avoid alcohol while taking oxycodone. Alcohol will greatly increase the
drowsiness and dizziness caused by oxycodone and could be dangerous.
‧ Oxycodone may increase the effects of other drugs that cause drowsiness,
including antidepressants, other antihistamines, other pain relievers,
anxiety medicines, seizure medicines, and muscle relaxants. Dangerous
sedation, dizziness, or drowsiness may occur if oxycodone is taken with any
of these medications.
‧ Never take more oxycodone than is prescribed for you. Taking too much
oxycodone could result in serious side effects, even death. If your pain is
not being adequately treated, talk to your doctor.
‧ Do not share this medication with anyone else.
What is oxycodone?
‧ Oxycodone is in a class of drugs called narcotic analgesics. It is a
pain reliever.
‧ Oxycodone is used to treat moderate-to-severe pain.
‧ Oxycodone may also be used for purposes other than those listed in this
medication guide.
Who should not take oxycodone?
‧ Oxycodone is habit forming and should only be used under close
supervision by patients with an alcohol or drug addiction.
‧ Before taking this medication, tell your doctor if you have
· kidney disease;
· liver disease;
· asthma;
· urinary retention;
· an enlarged prostate;
· hypothyroidism;
· seizures or epilepsy;
· gallbladder disease;
· a head injury; or
· Addison's disease.
‧ You may not be able to take oxycodone, or you may require a dosage
adjustment or special monitoring during treatment if you have any of the
conditions listed above.
‧ Oxycodone is in the FDA pregnancy category B. This means that it is
unlikely to cause birth defects. However, oxycodone may cause addiction and
withdrawal symptoms, difficulty breathing, as well as other harmful effects
in a newborn baby when taken during pregnancy. Do not take oxycodone without
first talking to your doctor if you are pregnant.
‧ Oxycodone may cause addiction and withdrawal symptoms, difficulty
breathing, and sedation in a nursing infant. Do not take oxycodone without
first talking to your doctor if you are breast-feeding a baby.
How should I take oxycodone?
‧ Take oxycodone exactly as directed by your doctor. If you do not
understand these directions, ask your pharmacist, nurse, or doctor to explain
them to you.
‧ Take each dose with a full glass of water.
‧ Oxycodone can be taken with food or milk if stomach upset occurs.
‧ Never take more oxycodone than is prescribed for you. Taking too much
oxycodone could result in serious side effects, even death. If your pain is
not being adequately treated, talk to your doctor.
‧ Do not crush, chew, or break controlled-release forms of oxycodone such
as Oxycontin. Swallow them whole. They are specially formulated to release
oxycodone slowly into your system. Breaking them would cause too much drug to
be released into the blood at one time leading to a potentially fatal dose of
oxycodone.
‧ Occasionally, empty Oxycontin tablets may be passed out in the stool.
This is not a problem. The active medication has been absorbed in the body
and the empty tablet shell may appear in the stool.
‧ To ensure that you get a correct dose, measure the liquid form of
oxycodone with a special dose-measuring spoon or cup, not with a regular
table spoon. If you do not have a dose-measuring device, ask your pharmacist
where you can get one.
‧ Do not stop taking oxycodone suddenly if you have been taking it
continuously for more than 5 to 7 days. Stopping suddenly could cause
withdrawal symptoms and make you uncomfortable. Your doctor may want to
gradually reduce the dose.
‧ Increasing the amount of fiber and water (six to eight full glasses) in
your diet may alleviate constipation.
‧ Do not share this medication with anyone else.
‧ Store oxycodone at room temperature away from moisture and heat and out
of the reach of children. When treatment with oxycodone is no longer needed,
any remaining medication should be destroyed by flushing down the toilet.
What happens if I miss a dose?
‧ Take the missed dose as soon as you remember. Do not take a double dose
of this medication. Wait the prescribed amount of time before taking the next
dose.
What happens if I overdose?
‧ Seek emergency medical attention.
‧ Symptoms of an oxycodone overdose include slow breathing, seizures,
dizziness, weakness, loss of consciousness, coma, confusion, tiredness, cold
and clammy skin, and small pupils.
What should I avoid while taking oxycodone?
‧ Avoid alcohol while taking oxycodone. Alcohol will greatly increase the
drowsiness and dizziness caused by oxycodone and could be dangerous.
‧ Oxycodone may increase the effects of other drugs that cause drowsiness,
including antidepressants, other antihistamines, other pain relievers,
anxiety medicines, seizure medicines, and muscle relaxants. Dangerous
sedation, dizziness, or drowsiness may occur if oxycodone is taken with any
of these medications.
‧ Use caution when driving, operating machinery, or performing other
hazardous activities. Oxycodone will cause drowsiness or dizziness. If you
experience drowsiness or dizziness, avoid these activities.
What are the possible side effects of oxycodone?
‧ If you experience any of the following serious side effects, stop taking
oxycodone and seek emergency medical attention or contact your doctor
immediately:
· an allergic reaction (difficulty breathing; closing of your throat;
swelling of your lips, tongue, or face; or hives);
· slow, weak breathing;
· seizures;
· cold, clammy skin;
· severe weakness or dizziness; or
· unconsciousness.
‧ Other, less serious side effects may be more likely to occur. Continue
to take oxycodone and talk to your doctor if you experience
· constipation;
· dry mouth, nausea, vomiting, or decreased appetite;
· dizziness, tiredness, or lightheadedness;
· muscle twitches;
· sweating;
· itching;
· decreased urination; or
· decreased sex drive.
‧ Do not stop taking oxycodone suddenly if you have been taking it
continuously for more than 5 to 7 days. Stopping suddenly could cause
withdrawal symptoms and make you uncomfortable. Your doctor may want to
gradually reduce the dose.
‧ Side effects other than those listed here may also occur. Talk to your
doctor about any side effect that seems unusual or that is especially
bothersome.
What other drugs will affect oxycodone?
‧ Oxycodone may increase the effects of other drugs that cause drowsiness,
including antidepressants, other antihistamines, pain relievers, anxiety
medicines, seizure medicines, and muscle relaxants. Dangerous sedation,
dizziness, or drowsiness may occur if oxycodone is taken with any of these
medications.
‧ Drugs other than those listed here may also interact with oxycodone.
Talk to your doctor and pharmacist before taking any prescription or
over-the-counter medicines.
Where can I get more information?
‧ Your pharmacist has additional information about oxycodone written for
health professionals that you may read.
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‧ Remember, keep this and all other medicines out of the reach of
children, never share your medicines with others, and use this medication
only for the indication prescribed.
‧ Every effort has been made to ensure that the information provided by
Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no
guarantee is made to that effect. Drug information contained herein may be
time sensitive. Multum information has been compiled for use by healthcare
practitioners and consumers in the United States and therefore Multum does
not warrant that uses outside of the United States are appropriate, unless
specifically indicated otherwise. Multum's drug information does not endorse
drugs, diagnose patients or recommend therapy. Multum's drug information is
an informational resource designed to assist licensed healthcare
practitioners in caring for their patients and/or to serve consumers viewing
this service as a supplement to, and not a substitute for, the expertise,
skill, knowledge and judgment of healthcare practitioners. The absence of a
warning for a given drug or drug combination in no way should be construed to
indicate that the drug or drug combination is safe, effective or appropriate
for any given patient. Multum does not assume any responsibility for any
aspect of healthcare administered with the aid of information Multum
provides. The information contained herein is not intended to cover all
possible uses, directions, precautions, warnings, drug interactions, allergic
reactions, or adverse effects. If you have questions about the drugs you are
taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2003 Cerner Multum, Inc. Version: 5.02. Revision Date: 2/14/03.
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