Re: [討論] 有關於賀寶芙的事嗎?
※ [本文轉錄自 Gossiping 看板]
作者: nikeman (nikeman) 看板: Gossiping
標題: Re: [討論] 有關於賀寶芙的事嗎?
時間: Fri Sep 21 21:54:38 2007
※ 引述《apa9394 (委員長老虎)》之銘言：
: 最新一期的肝病學期刊登出來說Herbalife的幾樣產品有肝毒性的報告 是人的...
: 是瑞士的醫院發的
: 這個期刊在肝病學領域是排第3的 IF4點多...
: 很多人在猜是indication的問題 尚在釐清中
: http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=17692989&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum
: http://0rz.tw/0536F
: J Hepatol. 2007 Oct;47(4):521-6. Epub 2007 Jul 24.
: Herbal does not mean innocuous: Ten cases of severe hepatotoxicity associated
: with dietary supplements from Herbalife((R)) products.Schoepfer AM, Engel A,
: Fattinger K, Marbet UA, Criblez D, Reichen J, Zimmermann A, Oneta CM.
: University Hospital of Bern, Gastroenterology Clinic, Bern, Switzerland.
草本並不能和無毒劃上等號。有10件嚴重的肝毒素病例是來自服用賀寶芙的減重產品。
(然後是研究者的名字: 一堆瑞士人)
: BACKGROUND/AIMS: Herbal agents are popular and perceived as safe because they
: are supposedly 'natural'. We report 10 cases of toxic hepatitis implicating
: Herbalife((R)) products. METHODS: To determine the prevalence and outcome of
: hepatotoxicity due to Herbalife((R)) products. A questionnaire was sent to all
: public Swiss hospitals. Reported cases were subjected to causality assessment
: using the CIOMS criteria. RESULTS: Twelve cases of toxic hepatitis implicating
: Herbalife((R)) preparations (1998-2004)
現在的草本的代餐食品非常流行，大多數人都認為它們是"天然"的而吃得很安心。
我們呈報10件和賀寶芙產品相關的肝炎中毒案例。
方法: 為確定肝毒素的普遍程度以及病灶乃來自賀寶芙產品，所有瑞士境內的公立醫院
將會收到相關問卷。呈報的案例將由 CIOMS 的標準進行病患評估。
(CIOMS = council for international organizations of medical sciences
www.cioms.ch)
: were retrieved, 10 sufficiently documented to permit causality analysis.
: Median age of patients was 51 years (range 30-69) and latency to onset was 5
: months (0.5-144). Liver biopsy (7/10) showed hepatic necrosis, marked
: lymphocytic/eosinophilic infiltration and cholestasis in five patients.
: One patient with fulminant liver failure was successfully transplanted; the
: explant showed giant cell hepatitis. Sinusoidal obstruction syndrome was
: observed in one case. Three patients without liver biopsy presented
: with hepatocellular (2) or mixed (1) liver injury. Causality assessment of
: adverse drug reaction was classified as certain in two, probable in seven and
: possible in one case(s), respectively. CONCLUSIONS: We present a case series
: of toxic hepatitis implicating Herbalife((R)) products. Liver toxicity may be
: severe. A more detailed declaration of components and pro-active role of
: regulatory agencies would be desirable.
結果: 12件肝炎性中毒的案例指向病因為賀寶芙的產品配方出了問題。而有10件完整的
病例報告允許我們作進一步分析。大多數的病患是中年人，歲數從30至69歲不等，平均
年齡為51歲。肝病毒潛伏期平均有5個月。有5個病例的肝組織切片顯示出肝壞疽，淋巴
球嗜紅潤透，以及膽汁阻塞。1個病例有猛爆性肝衰竭，已經完成肝臟移植；此例的肝切
片出現巨大的細胞性肝炎。其中有一例出現肝竇狀隙阻塞症候群。有三例缺少肝切片的
病患出現肝臟膨脹脫出，或混合性肝損傷。由逆向施藥測試的病例評估分成三類，各為
兩名、七名、與一名病例。
結論: 我們所呈現的肝毒素病案例病因指向賀寶芙的產品。肝臟中毒可以是非常嚴重的。
更詳細的食品內容標示，以及管理良好的直銷商能否扮演好具前瞻性的腳色，是賀寶芙必
須加強執行的。
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若有誤請指正
醫學用語請相關科系加註
我之前去賀氏早餐店吃了快半年
現在覺得非常害怕說
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