[問題] 乳癌檢驗報告相關問題
家母於5年前罹患乳癌(左乳)，當時為第一期。
後續經化療6次，放療等，去年8月還歡慶終於抗癌成功。
沒想到前幾天於定期檢驗(2/19)時，醫生觸診又摸到疑似腫瘤的怪東西。
這次為右乳。
立即由醫生安排進行粗針穿刺(2/20)。
於剛剛(2/23)查詢健保快易通的報告如下
The specimen submitted consists of six tissue fragments measuring up to
0.8x0.1x0.1 cm in size, fixed in formalin. Grossly, they are yellow and
elastic. All for one section and labeled as A1;Microscopically, the breast
shows neoplastic tumor cells with hyperchromasia, nuclear pleomorphism and
brisk mitotic figures arranged in solid nested pattern.
Immunohistochemically, the tumor cells show E-cadherin(+) and CK5/6(-).
Immunostain of p63 shows preserved myoepithelial cells around the tumor
nests. Taken together, high grade ductal carcinoma in situ is diagnosed. The
pathologic diagnosis has been discussed and confirmed by Peer Slide Review.
Immunohistochemical Study * ER: Negative (0%) [Leica Biosystems Estrogen
Receptor (Clone 6F11) mouse monoclonal antibody] * PR: Positive (35%, weak to
moderate) [Leica Biosystems Progesterone Receptor (Clone 16) mouse monoclonal
antibody
我想問3個問題
1. 如果我沒有理解錯誤的話，家母應為DCIS，0期的原位癌。
0期原位癌，到底是癌症嗎? 為何又說有檢驗到癌細胞?
2. 0期原位癌，有分等級嗎?這邊看到的是high grade
應該可以理解為比較不好的原位癌嗎?
3. 5年前，家母乳癌一期時，可以看到ER、PR、Her2以及ki67等數值。
但這次的報告，僅有看到ER為negtive、PR為弱到中陽性。
沒有看到Her2以及ki67的數值。
是否因為是原位癌，就沒有這些數值?
以上3個問題，可能再麻煩大家可以一起討論嗎?
感激不盡。
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