代po[徵才] UT Southwestern Medical Center博士後研究員
UT Southwestern Medical Center 徵求博士後研究員
職缺說明如下:
Postdoctoral Fellow in Transcription, Chromatin, Epigenetics, HPV, Molecular
Virology, Cancer Biology, and Small Compound Inhibitors Research Area:
Molecular Virology, Cancer Biology, Transcription, Chromatin, Gene Regulation,
Epigenetic Control, and Posttranslational Modification A postdoctoral training
position is available in the laboratory of Dr. Cheng-Ming Chiang, PhD
(https://profiles.utsouthwestern.edu/profile/95126/cheng-ming-chiang.html ) in
the Simmons Comprehensive Cancer Center at UT Southwestern Medical Center to
study breast cancer, human papillomavirus (HPV), mechanism of chromatin-dependent transcription, posttranslational modification of transcription factors,
cofactors and the general transcription machinery, cancer biology, and small
compound development.
Our current interest is to understand the molecular basis of the epigenetic
reader protein BRD4 in transcription programming, DNA repair, and cancer
pathway selectivity, and further develop small compound inhibitors to block
the oncogenic function of BRD4 using biochemical, molecular, genetic,
chemical biology, and genomic approaches with in vitro-reconstituted
chromatin transcription, cell-based, and inducible knockout and knock-in
transgenic mouse disease models. Breast cancer and HPV are two disease models
presently pursued in the lab. Applicants with a recent Ph.D. degree and a
strong background in transcription, chromatin, protein biochemistry, molecular
biology, virology, chemical biology, mouse models, genomics, and proteomics
are encouraged to apply.
Expertise in animal work is preferred but not essential.
Information on our postdoctoral training program and benefits can be found in
our Postdoc Handbook or at http://www.utsouthwestern.edu/postdocs.
Interested individuals should send a CV, statement of interests, and a list
of three references to:
Cheng-Ming Chiang, PhD
UT Southwestern Medical Center
5323 Harry Hines Blvd.
Dallas, TX 75390-8807
Cheng-ming.chiang@utsouthwestern.edu
實驗室近期發表:
Opposing Functions of BRD4 Isoforms in Breast Cancer
https://www.sciencedirect.com/science/article/abs/pii/S1097276520302768
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※ 編輯: vivitune (42.72.187.1 臺灣), 05/30/2020 23:37:07